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The product is dihydropyridine calcium antagonist with the characteristic of lipophilicity. It can be connected with dihydropyridine locus in L-type calcium channel in smooth muscle cytomembrane. It can control the  transmembrane influx while Ca2+ passes L-type calcium channel that can relax or expand smooth muscle to reduce pressure. Also, it can control the  transmembrane influx while Ca2+ passes N-type calcium channel in the smooth muscle of  sympathetic nerve that can control the releasing and sympathetic activity while nerve endings goes to methylepinephrine.
The product is the national second type of new drug. It is one kind of new dihydropyridine calcium antagonist which has L-type and N-type calcium channel (retardation). It is used to treat primary hypertension.

 

 

 
 
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